Biosynthesis of Membrane Teichoic Acid
نویسندگان
چکیده
منابع مشابه
Biosynthesis of the wall teichoic acid in Bacillus licheniformis.
1. The biosynthesis of the wall teichoic acid, poly(glycerol phosphate glucose), has been studied with a particulate membrane preparation from Bacillus licheniformis A.T.C.C. 9945. The precursor CDP-glycerol supplies glycerol phosphate residues, whereas UDP-glucose supplies only glucose to the repeating structure of the polymer. 2. Synthesis proceeds through polyprenol phosphate derivatives, an...
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Bifidobacteria are colonizers of the human gut, where they are interacting with their host as well as with other members of the intestinal microbiota. Teichoic acids (TAs) have previously been shown to play an important role in modulating microbe-host interactions in the human gut. However, so far, there is a paucity of information regarding the presence of TAs in the cell envelope of bifidobac...
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The biosynthetic enzymes involved in wall teichoic acid biogenesis in Grampositive bacteria have been the subject of renewed investigation in recent years with the benefit of modem tools of biochemistry and genetics. Nevertheless, there have been only limited investigations into the enzymes that glycosylate wall teichoic acid. Decades-old experiments in the model Gram-positive bacterium, Bacill...
متن کاملStreptococcal Teichoic Acid
Teichoic acid-like material extracted by cold trichloroacetic acid from lyophilized whole cells of streptococci from groups A, D, E, 0, and T was shown to give a positive precipitin reaction with group antisera. Similar material from cells of groups B, C, F, G, H, K, L, M, N, P, Q, R, and S did not give a positive reaction with group antisera. The group A material also reacted with anti-E serum...
متن کاملBiosynthesis of the Unique Wall Teichoic Acid of Staphylococcus aureus Lineage ST395
ABSTRACT The major clonal lineages of the human pathogen Staphylococcus aureus produce cell wall-anchored anionic poly-ribitol-phosphate (RboP) wall teichoic acids (WTA) substituted with d-Alanine and N-acetyl-d-glucosamine. The phylogenetically isolated S. aureus ST395 lineage has recently been found to produce a unique poly-glycerol-phosphate (GroP) WTA glycosylated with N-acetyl-d-galactosam...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)44027-1